Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM123373'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM123373 (US8742106, 6.13) Show SMILES C[C@H](NC(=O)COc1cc(c2c(nn(C)c2n1)C1CC1)C(F)(F)F)c1ccc(C)cc1 |r| Show InChI InChI=1S/C22H23F3N4O2/c1-12-4-6-14(7-5-12)13(2)26-17(30)11-31-18-10-16(22(23,24)25)19-20(15-8-9-15)28-29(3)21(19)27-18/h4-7,10,13,15H,8-9,11H2,1-3H3,(H,26,30)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	14	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...				US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW
					More data for this Ligand-Target Pair