Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM163944'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM163944 (US9062078, 75 | US9475819, 75 | US9637496, 75 | US...) Show SMILES CCOc1ccc2cccnc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2 |TLB:21:20:18.17:15| Show InChI InChI=1S/C24H25N3O3/c1-2-29-20-11-8-16-6-5-13-26-23(16)22(20)24(28)27-18-9-10-19(27)17(14-18)15-30-21-7-3-4-12-25-21/h3-8,11-13,17-19H,2,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	220	-39.9	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM163944 (US9062078, 75 | US9475819, 75 | US9637496, 75 | US...) Show SMILES CCOc1ccc2cccnc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2 |TLB:21:20:18.17:15| Show InChI InChI=1S/C24H25N3O3/c1-2-29-20-11-8-16-6-5-13-26-23(16)22(20)24(28)27-18-9-10-19(27)17(14-18)15-30-21-7-3-4-12-25-21/h3-8,11-13,17-19H,2,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM163944 (US9062078, 75 | US9475819, 75 | US9637496, 75 | US...) Show SMILES CCOc1ccc2cccnc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2 |TLB:21:20:18.17:15| Show InChI InChI=1S/C24H25N3O3/c1-2-29-20-11-8-16-6-5-13-26-23(16)22(20)24(28)27-18-9-10-19(27)17(14-18)15-30-21-7-3-4-12-25-21/h3-8,11-13,17-19H,2,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	220	-39.9	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM163944 (US9062078, 75 | US9475819, 75 | US9637496, 75 | US...) Show SMILES CCOc1ccc2cccnc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2 |TLB:21:20:18.17:15| Show InChI InChI=1S/C24H25N3O3/c1-2-29-20-11-8-16-6-5-13-26-23(16)22(20)24(28)27-18-9-10-19(27)17(14-18)15-30-21-7-3-4-12-25-21/h3-8,11-13,17-19H,2,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	220	-39.9	n/a	n/a	n/a	n/a	n/a	n/a	40
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair