Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM240136'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM240136 (US9403813, 41) Show SMILES CN(C)c1nc(C(=O)N2CC[C@H]2c2nc(no2)-c2ccccc2OC(F)(F)F)c(s1)-c1ccccc1 Show InChI InChI=1S/C24H20F3N5O3S/c1-31(2)23-28-18(19(36-23)14-8-4-3-5-9-14)22(33)32-13-12-16(32)21-29-20(30-35-21)15-10-6-7-11-17(15)34-24(25,26)27/h3-11,16H,12-13H2,1-2H3/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9403813 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RS2
					More data for this Ligand-Target Pair