Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM386887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM386887 (US10287305, Example 338 | US10508083, Example 338 ...) Show SMILES COC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1COC1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C20H30N2O5S/c1-26-20(23)22-12-6-9-18(21-28(2,24)25)19(22)14-27-17-11-10-16(13-17)15-7-4-3-5-8-15/h3-5,7-8,16-19,21H,6,9-14H2,1-2H3/t16?,17?,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...				J Med Chem 50: 2213-24 (2007) BindingDB Entry DOI: 10.7270/Q2Z321Z2
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM386887 (US10287305, Example 338 | US10508083, Example 338 ...) Show SMILES COC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1COC1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C20H30N2O5S/c1-26-20(23)22-12-6-9-18(21-28(2,24)25)19(22)14-27-17-11-10-16(13-17)15-7-4-3-5-8-15/h3-5,7-8,16-19,21H,6,9-14H2,1-2H3/t16?,17?,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
TBA					Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CZ3BCW
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM386887 (US10287305, Example 338 | US10508083, Example 338 ...) Show SMILES COC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1COC1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C20H30N2O5S/c1-26-20(23)22-12-6-9-18(21-28(2,24)25)19(22)14-27-17-11-10-16(13-17)15-7-4-3-5-8-15/h3-5,7-8,16-19,21H,6,9-14H2,1-2H3/t16?,17?,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...				US Patent US10508083 (2019) BindingDB Entry DOI: 10.7270/Q29S1TD1
					More data for this Ligand-Target Pair