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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxidized low-density lipoprotein receptor 1' and Ligand = 'BDBM454357'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxidized low-density lipoprotein receptor 1


(Bovine)		BDBM454357
PNG
(US10717734, Compound 33)
Show SMILES CC(C)c1c(Cc2ccc(cc2)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN
Show InChI InChI=1S/C22H26FN3O2S/c1-15(2)22-19(13-16-6-8-18(9-7-16)29(3,27)28)21-20(5-4-12-25-21)26(22)14-17(23)10-11-24/h4-10,12,15H,11,13-14,24H2,1-3H3/b17-10-
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>3.00E+5n/an/an/an/an/an/a



Pharmaxis Ltd.

US Patent


Assay Description
LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...

US Patent US10717734 (2020)


BindingDB Entry DOI: 10.7270/Q25T3PHK
More data for this
Ligand-Target Pair