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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxoeicosanoid receptor 1' and Ligand = 'BDBM50465681'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxoeicosanoid receptor 1


(Homo sapiens (Human))		BDBM50465681
PNG
(CHEMBL4277299)
Show SMILES CC(CC(O)=O)CC(=O)n1c(CCCCCCc2ccccc2)cc2ccc(Cl)cc12
Show InChI InChI=1S/C26H30ClNO3/c1-19(16-26(30)31)15-25(29)28-23(17-21-13-14-22(27)18-24(21)28)12-8-3-2-5-9-20-10-6-4-7-11-20/h4,6-7,10-11,13-14,17-19H,2-3,5,8-9,12,15-16H2,1H3,(H,30,31)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...

J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair