Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM50192141'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50192141 (CHEMBL384298 | methyl 1-(4-(1,1,1,3,3,3-hexafluoro...) Show SMILES COC(=O)C1(CCCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C21H19F6NO3/c1-31-17(29)18(14-6-3-2-4-7-14)12-5-13-28(18)16-10-8-15(9-11-16)19(30,20(22,23)24)21(25,26)27/h2-4,6-11,30H,5,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Binding affinity to LXRalpha by radioligand displacement assay				Bioorg Med Chem Lett 16: 5231-7 (2006) Article DOI: 10.1016/j.bmcl.2006.06.081 BindingDB Entry DOI: 10.7270/Q2HD7V80
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50192141 (CHEMBL384298 | methyl 1-(4-(1,1,1,3,3,3-hexafluoro...) Show SMILES COC(=O)C1(CCCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C21H19F6NO3/c1-31-17(29)18(14-6-3-2-4-7-14)12-5-13-28(18)16-10-8-15(9-11-16)19(30,20(22,23)24)21(25,26)27/h2-4,6-11,30H,5,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Transactivation of LXRalpha by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 5231-7 (2006) Article DOI: 10.1016/j.bmcl.2006.06.081 BindingDB Entry DOI: 10.7270/Q2HD7V80
					More data for this Ligand-Target Pair