Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM50258172 (CHEMBL521811 | methyl 3-(4-(N-(3-chloro-4-(3,3,3-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
AstraZeneca R&D Södertälje Curated by ChEMBL | Assay Description Agonist activity at LXRalpha ligand binding domain by FRET based SRC1 recruitment assay | Bioorg Med Chem Lett 19: 2009-12 (2009) Article DOI: 10.1016/j.bmcl.2009.02.039 BindingDB Entry DOI: 10.7270/Q20C4VNS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM50258172 (CHEMBL521811 | methyl 3-(4-(N-(3-chloro-4-(3,3,3-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
AstraZeneca R&D Södertälje Curated by ChEMBL | Assay Description Agonist activity at human LXRalpha expressed in human SH-SY5Y cells cotransfected with Gal4-LBD after 24 hrs by luciferase reporter gene assay | Bioorg Med Chem Lett 19: 2009-12 (2009) Article DOI: 10.1016/j.bmcl.2009.02.039 BindingDB Entry DOI: 10.7270/Q20C4VNS | |||||||||||
More data for this Ligand-Target Pair |