Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM27167'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27167 (1H-indol-1-yl tertiary amine, 11 | {[2-chloro-3-(t...) Show SMILES Cc1cc(C)c2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)n[nH]c2n1 Show InChI InChI=1S/C33H32ClF3N4O/c1-22-19-23(2)38-31-29(22)32(40-39-31)42-18-10-17-41(20-26-15-9-16-28(30(26)34)33(35,36)37)21-27(24-11-5-3-6-12-24)25-13-7-4-8-14-25/h3-9,11-16,19,27H,10,17-18,20-21H2,1-2H3,(H,38,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
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