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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM27314'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27314
PNG
(indole derivative, 5i | tert-butyl 2-{2-[(3-cyanob...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccc(c1)C#N
Show InChI InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-26-10-5-4-8-21(26)17-27(32)22-12-11-20-15-24(16-23(20)14-22)31-37(34,35)25-9-6-7-19(13-25)18-30/h4-14,17,24,31H,15-16H2,1-3H3
PDB

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PC cid
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Similars
Article
PubMed
n/an/an/an/a 460n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair