Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM50316094'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50316094 (3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(tr...) Show SMILES CCc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3N2O2S/c1-3-20-22(29-21-9-5-8-19(23(21)28-20)24(25,26)27)16-12-10-15(11-13-16)17-6-4-7-18(14-17)32(2,30)31/h4-14H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human LXRbeta ligand binding domain				J Med Chem 53: 3296-304 (2010) Article DOI: 10.1021/jm100034x BindingDB Entry DOI: 10.7270/Q29W0FN8
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50316094 (3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(tr...) Show SMILES CCc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3N2O2S/c1-3-20-22(29-21-9-5-8-19(23(21)28-20)24(25,26)27)16-12-10-15(11-13-16)17-6-4-7-18(14-17)32(2,30)31/h4-14H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human recombinant LXRbeta ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assay				J Med Chem 53: 3296-304 (2010) Article DOI: 10.1021/jm100034x BindingDB Entry DOI: 10.7270/Q29W0FN8
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50316094 (3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(tr...) Show SMILES CCc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3N2O2S/c1-3-20-22(29-21-9-5-8-19(23(21)28-20)24(25,26)27)16-12-10-15(11-13-16)17-6-4-7-18(14-17)32(2,30)31/h4-14H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.59E+3	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human recombinant LXRalpha ligand binding domain in human HuH7 cells cotransfected with fused Gal4-DBD by transactivation assay				J Med Chem 53: 3296-304 (2010) Article DOI: 10.1021/jm100034x BindingDB Entry DOI: 10.7270/Q29W0FN8
					More data for this Ligand-Target Pair