Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM50390741'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390741 (CHEMBL2070364) Show SMILES CCn1cc(cn1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C25H26F3N3O3S/c1-4-30-18-20(16-29-30)14-15-24(32,25(26,27)28)21-10-12-22(13-11-21)31(17-19(2)3)35(33,34)23-8-6-5-7-9-23/h5-13,16,18-19,32H,4,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from GST-tagged LXRbeta ligand binding domai...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390741 (CHEMBL2070364) Show SMILES CCn1cc(cn1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C25H26F3N3O3S/c1-4-30-18-20(16-29-30)14-15-24(32,25(26,27)28)21-10-12-22(13-11-21)31(17-19(2)3)35(33,34)23-8-6-5-7-9-23/h5-13,16,18-19,32H,4,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LXRbeta ligand binding domain expressed in HEK293 cells coexpressing GAL4 assessed as decrease in [3H]N-(4-(1,1,1,3,3,3-hexafl...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair