Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM50390767'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390767 (CHEMBL2070465) Show SMILES CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CCC1)S(=O)(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C28H26F3NO5S2/c1-38(34,35)25-16-10-21(11-17-25)18-19-27(33,28(29,30)31)23-12-14-24(15-13-23)32(20-22-6-5-7-22)39(36,37)26-8-3-2-4-9-26/h2-4,8-17,22,33H,5-7,20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from GST-tagged LXRbeta ligand binding domai...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50390767 (CHEMBL2070465) Show SMILES CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CCC1)S(=O)(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C28H26F3NO5S2/c1-38(34,35)25-16-10-21(11-17-25)18-19-27(33,28(29,30)31)23-12-14-24(15-13-23)32(20-22-6-5-7-22)39(36,37)26-8-3-2-4-9-26/h2-4,8-17,22,33H,5-7,20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LXRbeta ligand binding domain expressed in HEK293 cells coexpressing GAL4 assessed as decrease in [3H]N-(4-(1,1,1,3,3,3-hexafl...				Bioorg Med Chem Lett 22: 5966-70 (2012) Article DOI: 10.1016/j.bmcl.2012.07.048 BindingDB Entry DOI: 10.7270/Q2PR7X24
					More data for this Ligand-Target Pair