Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM246970'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM246970 ((S)-3-(2,4-dichlorophenyl)-8-(5-fluoropyridin-2-yl...) Show SMILES C[C@H]1Cn2c(nnc2-c2ccc(F)cn2)-c2nnc(-c3ccc(Cl)cc3Cl)n12 |r| Show InChI InChI=1S/C18H12Cl2FN7/c1-9-8-27-16(14-5-3-11(21)7-22-14)24-25-17(27)18-26-23-15(28(9)18)12-4-2-10(19)6-13(12)20/h2-7,9H,8H2,1H3/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...				US Patent US10053463 (2018) BindingDB Entry DOI: 10.7270/Q2FT8P24
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM246970 ((S)-3-(2,4-dichlorophenyl)-8-(5-fluoropyridin-2-yl...) Show SMILES C[C@H]1Cn2c(nnc2-c2ccc(F)cn2)-c2nnc(-c3ccc(Cl)cc3Cl)n12 |r| Show InChI InChI=1S/C18H12Cl2FN7/c1-9-8-27-16(14-5-3-11(21)7-22-14)24-25-17(27)18-26-23-15(28(9)18)12-4-2-10(19)6-13(12)20/h2-7,9H,8H2,1H3/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...				US Patent US10053463 (2018) BindingDB Entry DOI: 10.7270/Q2FT8P24
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM246970 ((S)-3-(2,4-dichlorophenyl)-8-(5-fluoropyridin-2-yl...) Show SMILES C[C@H]1Cn2c(nnc2-c2ccc(F)cn2)-c2nnc(-c3ccc(Cl)cc3Cl)n12 |r| Show InChI InChI=1S/C18H12Cl2FN7/c1-9-8-27-16(14-5-3-11(21)7-22-14)24-25-17(27)18-26-23-15(28(9)18)12-4-2-10(19)6-13(12)20/h2-7,9H,8H2,1H3/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.7	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US10053463 (2018) BindingDB Entry DOI: 10.7270/Q2FT8P24
					More data for this Ligand-Target Pair