Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50374478'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50374478 (CHEMBL402614) Show SMILES Cc1cc(CC(=O)N2CCN(CC2c2ccccc2)C(NC#N)=Nc2ccccc2C)on1 |w:23.25| Show InChI InChI=1S/C25H26N6O2/c1-18-8-6-7-11-22(18)28-25(27-17-26)30-12-13-31(23(16-30)20-9-4-3-5-10-20)24(32)15-21-14-19(2)29-33-21/h3-11,14,23H,12-13,15-16H2,1-2H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assay				Bioorg Med Chem Lett 18: 2093-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.094 BindingDB Entry DOI: 10.7270/Q2HH6KXV
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50374478 (CHEMBL402614) Show SMILES Cc1cc(CC(=O)N2CCN(CC2c2ccccc2)C(NC#N)=Nc2ccccc2C)on1 |w:23.25| Show InChI InChI=1S/C25H26N6O2/c1-18-8-6-7-11-22(18)28-25(27-17-26)30-12-13-31(23(16-30)20-9-4-3-5-10-20)24(32)15-21-14-19(2)29-33-21/h3-11,14,23H,12-13,15-16H2,1-2H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assay				Bioorg Med Chem Lett 18: 2093-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.094 BindingDB Entry DOI: 10.7270/Q2HH6KXV
					More data for this Ligand-Target Pair