Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50410949'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50410949 (CHEMBL210835) Show SMILES FC(F)(F)c1cccc(c1Cl)-n1nnnc1Cc1cccnc1 Show InChI InChI=1S/C14H9ClF3N5/c15-13-10(14(16,17)18)4-1-5-11(13)23-12(20-21-22-23)7-9-3-2-6-19-8-9/h1-6,8H,7H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of calcium flux by FLIPR				J Med Chem 49: 3659-66 (2006) Article DOI: 10.1021/jm051202e BindingDB Entry DOI: 10.7270/Q2VD70P4
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50410949 (CHEMBL210835) Show SMILES FC(F)(F)c1cccc(c1Cl)-n1nnnc1Cc1cccnc1 Show InChI InChI=1S/C14H9ClF3N5/c15-13-10(14(16,17)18)4-1-5-11(13)23-12(20-21-22-23)7-9-3-2-6-19-8-9/h1-6,8H,7H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptake				J Med Chem 52: 3123-41 (2009) Article DOI: 10.1021/jm801528x BindingDB Entry DOI: 10.7270/Q2251KDR
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50410949 (CHEMBL210835) Show SMILES FC(F)(F)c1cccc(c1Cl)-n1nnnc1Cc1cccnc1 Show InChI InChI=1S/C14H9ClF3N5/c15-13-10(14(16,17)18)4-1-5-11(13)23-12(20-21-22-23)7-9-3-2-6-19-8-9/h1-6,8H,7H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of calcium flux by FLIPR				J Med Chem 49: 3659-66 (2006) Article DOI: 10.1021/jm051202e BindingDB Entry DOI: 10.7270/Q2VD70P4
					More data for this Ligand-Target Pair