Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50411872'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50411872 (CHEMBL271679) Show SMILES Clc1cccc(c1Cl)-n1ncnc1NCc1ccccc1 Show InChI InChI=1S/C15H12Cl2N4/c16-12-7-4-8-13(14(12)17)21-15(19-10-20-21)18-9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47.9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP-induced calcium flux by FLIPR assay				Bioorg Med Chem Lett 18: 2089-92 (2008) Article DOI: 10.1016/j.bmcl.2008.01.095 BindingDB Entry DOI: 10.7270/Q2ZW1N5R
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50411872 (CHEMBL271679) Show SMILES Clc1cccc(c1Cl)-n1ncnc1NCc1ccccc1 Show InChI InChI=1S/C15H12Cl2N4/c16-12-7-4-8-13(14(12)17)21-15(19-10-20-21)18-9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP-induced calcium flux by FLIPR assay				Bioorg Med Chem Lett 18: 2089-92 (2008) Article DOI: 10.1016/j.bmcl.2008.01.095 BindingDB Entry DOI: 10.7270/Q2ZW1N5R
					More data for this Ligand-Target Pair