Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50415886'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415886 (CHEMBL1096047) Show SMILES Cc1nn(Cc2cccnc2)c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C20H20ClFN4O/c1-13-18(14(2)26(25-13)12-15-4-3-7-23-10-15)9-20(27)24-11-16-5-6-17(22)8-19(16)21/h3-8,10H,9,11-12H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair