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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 2' and Ligand = 'BDBM330055'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
POU domain, class 2, transcription factor 2


(Homo sapiens (Human))		BDBM330055
PNG
((1R,4S,12aR)-7-hydroxy-6,8-dioxo-N—((R)-1-(2,...)
Show SMILES C[C@@H](NC(=O)c1cn2C[C@H]3[C@@H]4CC[C@@H](C4)N3C(=O)c2c(O)c1=O)c1c(F)cc(F)cc1F |THB:8:9:12.11:14,16:15:12.11:14|
Show InChI InChI=1S/C22H20F3N3O4/c1-9(17-14(24)5-11(23)6-15(17)25)26-21(31)13-7-27-8-16-10-2-3-12(4-10)28(16)22(32)18(27)20(30)19(13)29/h5-7,9-10,12,16,30H,2-4,8H2,1H3,(H,26,31)/t9-,10-,12+,16+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.83E+3n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...

US Patent US10689399 (2020)


BindingDB Entry DOI: 10.7270/Q2S185HX
More data for this
Ligand-Target Pair