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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 2' and Ligand = 'BDBM330056'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
POU domain, class 2, transcription factor 2


(Homo sapiens (Human))		BDBM330056
PNG
((1S,3R,4R,12aR)-3-fluoro-7-hydroxy-6,8-dioxo-N-(2,...)
Show SMILES Oc1c2C(=O)N3[C@@H]4C[C@@H](C[C@H]4F)[C@@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O |TLB:13:12:10.9:7,THB:11:10:12.5:7,3:5:10.9:7|
Show InChI InChI=1S/C21H17F4N3O4/c22-9-3-12(23)10(13(24)4-9)5-26-20(31)11-6-27-7-16-8-1-14(25)15(2-8)28(16)21(32)17(27)19(30)18(11)29/h3-4,6,8,14-16,30H,1-2,5,7H2,(H,26,31)/t8-,14-,15-,16+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...

US Patent US10689399 (2020)


BindingDB Entry DOI: 10.7270/Q2S185HX
More data for this
Ligand-Target Pair