Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 2' and Ligand = 'BDBM350833'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POU domain, class 2, transcription factor 2 (Homo sapiens (Human))	BDBM350833 (US9795602, Compound 39) Show SMILES CCN1[C@@H]2COCC[C@@H]2n2cc(C(=O)NCc3ccc(F)c(Cl)c3F)c(=O)c(O)c2C1=O |r| Show InChI InChI=1S/C21H20ClF2N3O5/c1-2-26-14-9-32-6-5-13(14)27-8-11(18(28)19(29)17(27)21(26)31)20(30)25-7-10-3-4-12(23)15(22)16(10)24/h3-4,8,13-14,29H,2,5-7,9H2,1H3,(H,25,30)/t13-,14+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...				US Patent US9795602 (2017) BindingDB Entry DOI: 10.7270/Q2K35WTB
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