Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 2' and Ligand = 'BDBM350834'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POU domain, class 2, transcription factor 2 (Homo sapiens (Human))	BDBM350834 (US9795602, Compound 12) Show SMILES CCN1[C@@H]2COCC[C@H]2n2cc(C(=O)NCc3c(F)cc(F)cc3F)c(=O)c(O)c2C1=O |r| Show InChI InChI=1S/C21H20F3N3O5/c1-2-26-16-9-32-4-3-15(16)27-8-12(18(28)19(29)17(27)21(26)31)20(30)25-7-11-13(23)5-10(22)6-14(11)24/h5-6,8,15-16,29H,2-4,7,9H2,1H3,(H,25,30)/t15-,16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...				US Patent US9795602 (2017) BindingDB Entry DOI: 10.7270/Q2K35WTB
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