BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Pancreatic triacylglycerol lipase' and Ligand = 'BDBM50269345'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Pancreatic triacylglycerol lipase


(Sus scrofa (Pig))		BDBM50269345
PNG
(CHEMBL4064504)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=C1/SC(=O)N(Cc2ccc(cc2)[N+]([O-])=O)C1=O)-c1ccccc1
Show InChI InChI=1S/C27H20N4O5S/c1-36-23-13-9-19(10-14-23)25-20(17-30(28-25)21-5-3-2-4-6-21)15-24-26(32)29(27(33)37-24)16-18-7-11-22(12-8-18)31(34)35/h2-15,17H,16H2,1H3/b24-15-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 9.40E+3n/an/an/an/an/an/a



Laboratory of Natural Drugs, Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS Pilani), Pilani Campus, Pilani 333 031, Rajasthan, India.

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate preincubated for 5 mins followed by substrate addition measured aft...

Bioorg Med Chem Lett 27: 3749-3754 (2017)


Article DOI: 10.1016/j.bmcl.2017.06.069
BindingDB Entry DOI: 10.7270/Q2FX7CZQ
More data for this
Ligand-Target Pair