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Found 1 hit Enz. Inhib. hit(s) with Target = 'Pantothenate kinase' and Ligand = 'BDBM188496'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Pantothenate kinase


(Mycobacterium tuberculosis ATCC 25618/H37Rv)		BDBM188496
PNG
(Biaryl 2b)
Show SMILES NC(=O)COc1ccc(c(CN2CCN(CC2)c2ccccn2)c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C25H25N5O2/c26-16-19-4-7-21(8-5-19)23-9-6-20(18-32-25(27)31)15-22(23)17-29-11-13-30(14-12-29)24-3-1-2-10-28-24/h1-10,15H,11-14,17-18H2,(H2,27,31)/p-1
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 550n/an/an/an/an/an/a



Uppsala University



Assay Description
Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...

J Biol Chem 288: 18260-70 (2013)


Article DOI: 10.1074/jbc.M113.476473
BindingDB Entry DOI: 10.7270/Q27H1HDX
More data for this
Ligand-Target Pair