Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Parathyroid hormone/parathyroid hormone-related peptide receptor' and Ligand = 'BDBM50522126'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50522126 (CHEMBL4465123) Show SMILES CC1(C)N=C(C2CCCCC2)c2ccc(cc2N(c2ccc(NCCNC3CCOCC3)cc2)C1=O)C#N |t:3| Show InChI InChI=1S/C31H39N5O2/c1-31(2)30(37)36(26-11-9-24(10-12-26)33-16-17-34-25-14-18-38-19-15-25)28-20-22(21-32)8-13-27(28)29(35-31)23-6-4-3-5-7-23/h8-13,20,23,25,33-34H,3-7,14-19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-indu...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115524 BindingDB Entry DOI: 10.7270/Q2H135J0
					More data for this Ligand-Target Pair
Parathyroid hormone/parathyroid hormone-related peptide receptor (Homo sapiens (Human))	BDBM50522126 (CHEMBL4465123) Show SMILES CC1(C)N=C(C2CCCCC2)c2ccc(cc2N(c2ccc(NCCNC3CCOCC3)cc2)C1=O)C#N |t:3| Show InChI InChI=1S/C31H39N5O2/c1-31(2)30(37)36(26-11-9-24(10-12-26)33-16-17-34-25-14-18-38-19-15-25)28-20-22(21-32)8-13-27(28)29(35-31)23-6-4-3-5-7-23/h8-13,20,23,25,33-34H,3-7,14-19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Antagonist activity at human PTHR1 expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-induced cAMP ac...				Bioorg Med Chem Lett 29: 2613-2616 (2019) Article DOI: 10.1016/j.bmcl.2019.07.052 BindingDB Entry DOI: 10.7270/Q2XW4P6F
					More data for this Ligand-Target Pair