Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidase (Staphylococcus aureus) | BDBM50378857 (CEFTOBIPROLE | Zeftera | Zevtera) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Inhibition of bocillin FL binding to methicillin-resistant Staphylococcus aureus OC 3726 penicillin-binding protein 2a | Antimicrob Agents Chemother 51: 2621-4 (2007) Article DOI: 10.1128/aac.00029-07 BindingDB Entry DOI: 10.7270/Q2VH5RN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50378857 (CEFTOBIPROLE | Zeftera | Zevtera) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universit£ Catholique de Louvain Curated by ChEMBL | Assay Description Binding affinity to Staphylococcus aureus ATCC 433000 PBP2a by western blotting at pH 7.4 in presence of 100 uM Bocillin FL | Antimicrob Agents Chemother 53: 2289-97 (2009) Article DOI: 10.1128/AAC.01135-08 BindingDB Entry DOI: 10.7270/Q2NZ88MK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50378857 (CEFTOBIPROLE | Zeftera | Zevtera) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Rockefeller University Curated by ChEMBL | Assay Description Inhibition of methicillin-resistant Staphylococcus aureus COL PBP2a by competitive assay | Antimicrob Agents Chemother 52: 2709-17 (2008) Article DOI: 10.1128/AAC.00266-08 BindingDB Entry DOI: 10.7270/Q2GH9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50378857 (CEFTOBIPROLE | Zeftera | Zevtera) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Universit£ Catholique de Louvain Curated by ChEMBL | Assay Description Binding affinity to Staphylococcus aureus ATCC 433000 PBP2a by western blotting at pH 5.5 in presence of 100 uM Bocillin FL | Antimicrob Agents Chemother 53: 2289-97 (2009) Article DOI: 10.1128/AAC.01135-08 BindingDB Entry DOI: 10.7270/Q2NZ88MK | |||||||||||
More data for this Ligand-Target Pair |