BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptide deformylase, mitochondrial' and Ligand = 'BDBM50542138'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptide deformylase, mitochondrial


(Homo sapiens (Human))		BDBM50542138
PNG
(CHEMBL4639327)
Show SMILES CCCC[C@H](CC(=O)NO)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1ccc(F)cn1 |r|
Show InChI InChI=1S/C20H27FN4O4/c1-2-3-4-13(9-17(26)24-29)19(28)25-12-20(7-8-20)10-15(25)18(27)23-16-6-5-14(21)11-22-16/h5-6,11,13,15,29H,2-4,7-10,12H2,1H3,(H,24,26)(H,22,23,27)/t13-,15+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.90n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...

J Med Chem 63: 6959-6978 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00079
BindingDB Entry DOI: 10.7270/Q2125X6C
More data for this
Ligand-Target Pair