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Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptide deformylase, mitochondrial' and Ligand = 'BDBM50542143'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptide deformylase, mitochondrial


(Homo sapiens (Human))		BDBM50542143
PNG
(CHEMBL4645936)
Show SMILES ONC(=O)C[C@@H](CC1CCCC1)C(=O)N1CC2(CC2)C[C@H]1C(=O)Nc1nccs1 |r|
Show InChI InChI=1S/C20H28N4O4S/c25-16(23-28)10-14(9-13-3-1-2-4-13)18(27)24-12-20(5-6-20)11-15(24)17(26)22-19-21-7-8-29-19/h7-8,13-15,28H,1-6,9-12H2,(H,23,25)(H,21,22,26)/t14-,15+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.70n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...

J Med Chem 63: 6959-6978 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00079
BindingDB Entry DOI: 10.7270/Q2125X6C
More data for this
Ligand-Target Pair