Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285709 (US10077289, Compound 17 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair |