Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase D' and Ligand = 'BDBM394281'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptidyl-prolyl cis-trans isomerase D (Homo sapiens (Human))	BDBM394281 (US9975902, Example 11) Show SMILES CCC1Oc2cc(ccc2NC1=O)C(C)NC(=O)CN1C(=O)[C@H]2[C@H]3CC[C@H](C3)[C@H]2C1=O |r| Show InChI InChI=1S/C23H27N3O5/c1-3-16-21(28)25-15-7-6-12(9-17(15)31-16)11(2)24-18(27)10-26-22(29)19-13-4-5-14(8-13)20(19)23(26)30/h6-7,9,11,13-14,16,19-20H,3-5,8,10H2,1-2H3,(H,24,27)(H,25,28)/t11?,13-,14+,16?,19-,20+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIC					Assay Description The binding capacity of the compounds was measured using a competition Fluorescence-Polarisation based assay with fluorescine labelled cyclosporin.				J Med Chem 52: 2724-32 (2009) BindingDB Entry DOI: 10.7270/Q26W9DD6
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