BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1' and Ligand = 'BDBM50234003'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1


(Homo sapiens (Human))		BDBM50234003
PNG
(CHEMBL4085308)
Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(C(=O)C=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@]5(C)CC[C@@]34C)[C@@]1(C)C=C(I)C(=O)[C@]2(C)C(=O)N1CCNCC1 |r,t:10,32|
Show InChI InChI=1S/C34H49IN2O3/c1-20-8-10-30(3)12-13-32(5)22(26(30)21(20)2)18-24(38)27-31(4)19-23(35)28(39)34(7,25(31)9-11-33(27,32)6)29(40)37-16-14-36-15-17-37/h18-21,25-27,36H,8-17H2,1-7H3/t20-,21+,25-,26+,27-,30-,31+,32-,33-,34-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.29E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of Pin1 (unknown origin) using Suc-Ala-Glu-cis-Pro-Phe-4-nitroanilide as substrate preincubated for 30 mins followed by substrate addition...

Eur J Med Chem 126: 910-919 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.089
BindingDB Entry DOI: 10.7270/Q23T9KGJ
More data for this
Ligand-Target Pair