Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Perforin-1' and Ligand = 'BDBM50235181'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Perforin-1 (Homo sapiens (Human))	BDBM50235181 (CHEMBL4084215) Show SMILES Cn1ccc2cc(ccc12)-c1ccc(s1)-c1cncc(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C24H17F2N3O2S2/c1-29-9-8-15-10-16(2-4-21(15)29)22-5-6-23(32-22)17-11-19(14-27-13-17)28-33(30,31)24-7-3-18(25)12-20(24)26/h2-14,28H,1H3	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 27: 1050-1054 (2017) Article DOI: 10.1016/j.bmcl.2016.12.057 BindingDB Entry DOI: 10.7270/Q2XS5XNH
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