Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Perforin-1 (Homo sapiens (Human)) | BDBM50235191 (CHEMBL4091967) | NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of recombinant perforin (unknown origin) assessed as decrease in lysis of 51Cr-labelled human Jurkat cells by measuring 51Cr release prein... | Bioorg Med Chem Lett 27: 1050-1054 (2017) Article DOI: 10.1016/j.bmcl.2016.12.057 BindingDB Entry DOI: 10.7270/Q2XS5XNH | |||||||||||
More data for this Ligand-Target Pair |