Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Perforin-1' and Ligand = 'BDBM50275013'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Perforin-1 (Homo sapiens (Human))	BDBM50275013 ((Z)-1-((1H-Indol-2-yl)methylene)-6-methyl-4-thioxo...) Show SMILES Cc1cc2\C(OC(=O)c2c(=S)[nH]1)=C\c1cc2ccccc2[nH]1 Show InChI InChI=1S/C17H12N2O2S/c1-9-6-12-14(21-17(20)15(12)16(22)18-9)8-11-7-10-4-2-3-5-13(10)19-11/h2-8,19H,1H3,(H,18,22)/b14-8-	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant perforin (unknown origin)-mediated lysis of human Jurkat T cells by 51Cr release assay				J Med Chem 51: 7614-24 (2009) Article DOI: 10.1021/jm801063n BindingDB Entry DOI: 10.7270/Q24F1QK1
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