Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Perforin-1' and Ligand = 'BDBM50275093'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Perforin-1 (Homo sapiens (Human))	BDBM50275093 ((Z)-1-((5-Methoxybenzo[b]thiophen-3-yl)methylene)-...) Show SMILES COc1ccc2scc(\C=C3/OC(=O)c4c3cc(C)[nH]c4=S)c2c1 Show InChI InChI=1S/C18H13NO3S2/c1-9-5-13-14(22-18(20)16(13)17(23)19-9)6-10-8-24-15-4-3-11(21-2)7-12(10)15/h3-8H,1-2H3,(H,19,23)/b14-6-	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant perforin (unknown origin)-mediated lysis of human Jurkat T cells by 51Cr release assay				J Med Chem 51: 7614-24 (2009) Article DOI: 10.1021/jm801063n BindingDB Entry DOI: 10.7270/Q24F1QK1
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