Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Perforin-1' and Ligand = 'BDBM50276478'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Perforin-1 (Homo sapiens (Human))	BDBM50276478 (CHEMBL4163775) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccccn1)-c1ccc(s1)-c1ccc2C(=O)N(C)Cc2c1 Show InChI InChI=1S/C25H21N3O4S2/c1-28-15-18-13-16(6-8-19(18)25(28)29)21-10-11-22(33-21)17-7-9-20(32-2)23(14-17)34(30,31)27-24-5-3-4-12-26-24/h3-14H,15H2,1-2H3,(H,26,27)	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...				Eur J Med Chem 137: 139-155 (2017) Article DOI: 10.1016/j.ejmech.2017.05.048 BindingDB Entry DOI: 10.7270/Q21R6T15
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