Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Perforin-1' and Ligand = 'BDBM50276543'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Perforin-1 (Homo sapiens (Human))	BDBM50276543 (CHEMBL4172029) Show SMILES CN1Cc2cc(ccc2C1=O)-c1ccc(s1)-c1cncc(NS(=O)(=O)c2ccc(F)cc2C)c1 Show InChI InChI=1S/C25H20FN3O3S2/c1-15-9-19(26)4-8-24(15)34(31,32)28-20-11-17(12-27-13-20)23-7-6-22(33-23)16-3-5-21-18(10-16)14-29(2)25(21)30/h3-13,28H,14H2,1-2H3	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell additio...				Eur J Med Chem 137: 139-155 (2017) Article DOI: 10.1016/j.ejmech.2017.05.048 BindingDB Entry DOI: 10.7270/Q21R6T15
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