BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Period circadian protein homolog 2' and Ligand = 'BDBM356649'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356649 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	527	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020) BindingDB Entry DOI: 10.7270/Q2C250HB
Synchronicity Pharma, Inc. US Patent					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356649 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	527	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
Reset Therapeutics, Inc. US Patent					More data for this Ligand-Target Pair