Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Period circadian protein homolog 2' and Ligand = 'BDBM356676'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356676 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CCN1CCCN(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1=O Show InChI InChI=1S/C22H25F2N3O2/c1-3-25-9-4-10-26(21(25)28)13-22(2,29)14-27-19-7-5-15(23)11-17(19)18-12-16(24)6-8-20(18)27/h5-8,11-12,29H,3-4,9-10,13-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020) BindingDB Entry DOI: 10.7270/Q2C250HB
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356676 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CCN1CCCN(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1=O Show InChI InChI=1S/C22H25F2N3O2/c1-3-25-9-4-10-26(21(25)28)13-22(2,29)14-27-19-7-5-15(23)11-17(19)18-12-16(24)6-8-20(18)27/h5-8,11-12,29H,3-4,9-10,13-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair