Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Period circadian protein homolog 2' and Ligand = 'BDBM356693'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356693 (1-cyclopropyl-3-(3- (3,6-difluoro-9H- carbazol-9-y...) Show SMILES OC(CN1CCN(C2CC2)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C21H21F2N3O2/c22-13-1-5-19-17(9-13)18-10-14(23)2-6-20(18)26(19)12-16(27)11-24-7-8-25(21(24)28)15-3-4-15/h1-2,5-6,9-10,15-16,27H,3-4,7-8,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	527	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020) BindingDB Entry DOI: 10.7270/Q2C250HB
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356693 (1-cyclopropyl-3-(3- (3,6-difluoro-9H- carbazol-9-y...) Show SMILES OC(CN1CCN(C2CC2)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C21H21F2N3O2/c22-13-1-5-19-17(9-13)18-10-14(23)2-6-20(18)26(19)12-16(27)11-24-7-8-25(21(24)28)15-3-4-15/h1-2,5-6,9-10,15-16,27H,3-4,7-8,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	527	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair