Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (Homo sapiens (Human)) | BDBM50015358 (CHEMBL417844 | N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity measured as apparent dissociation constant against Polyamine oxidase (PAO) from pig liver | J Med Chem 28: 1-2 (1985) BindingDB Entry DOI: 10.7270/Q2445KHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (Mus musculus) | BDBM50015358 (CHEMBL417844 | N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute Curated by ChEMBL | Assay Description Tested for in vitro binding affinity against polyamine oxidase after intraperitoneal administration in the rat liver | J Med Chem 33: 1369-75 (1990) BindingDB Entry DOI: 10.7270/Q2RN38F8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |