Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase catalytic subunit type 3' and Ligand = 'BDBM346209'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM346209 (US10202373, Compound I-22 | US10202373, Example 5) Show SMILES CC(=O)Nc1cc(ccn1)-c1cncc2n(ncc12)S(=O)(=O)C1CC1 Show InChI InChI=1S/C16H15N5O3S/c1-10(22)20-16-6-11(4-5-18-16)13-7-17-9-15-14(13)8-19-21(15)25(23,24)12-2-3-12/h4-9,12H,2-3H2,1H3,(H,18,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
MILLENNIUM PHARMACEUTICALS, INC. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US10202373 (2019) BindingDB Entry DOI: 10.7270/Q2FN18BC
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