Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM226298'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM226298 (US9321790, 110) Show SMILES FC(F)(F)[C@@H]1CCn2c(nc(cc2=O)N2C[C@@H]3C[C@H]2CO3)N1CC(=O)N1CCOCC1 |TLB:10:14:19.20:17| Show InChI InChI=1S/C19H24F3N5O4/c20-19(21,22)14-1-2-25-16(28)8-15(26-9-13-7-12(26)11-31-13)23-18(25)27(14)10-17(29)24-3-5-30-6-4-24/h8,12-14H,1-7,9-11H2/t12-,13-,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
Sanofi US Patent					Assay Description The compounds according to the invention underwent pharmacological trials to measure the selectivity toward human lipid kinases and especially human ...				US Patent US9321790 (2016) BindingDB Entry DOI: 10.7270/Q2KD1WSG
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