Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50537410'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50537410 (CHEMBL4535132) Show SMILES COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCN(CC1)S(=O)(=O)CCN1CCCCC1)N1CCOCC1 Show InChI InChI=1S/C27H37F2N9O4S/c1-41-21-7-5-6-20-22(21)30-24(23(28)29)38(20)27-32-25(31-26(33-27)36-14-17-42-18-15-36)35-10-12-37(13-11-35)43(39,40)19-16-34-8-3-2-4-9-34/h5-7,23H,2-4,8-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...				Bioorg Med Chem 27: 1529-1545 (2019) Article DOI: 10.1016/j.bmc.2019.02.050 BindingDB Entry DOI: 10.7270/Q2XW4P9S
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