Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform' and Ligand = 'BDBM259459'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM259459 (US9512114, 24 | US9657007, Example 24) Show SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(Cl)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C21H20ClN7O2/c1-10(26-19-17(18(23)24-9-25-19)20-27-11(2)28-31-20)15-8-12-4-3-5-14(22)16(12)21(30)29(15)13-6-7-13/h3-5,8-10,13H,6-7H2,1-2H3,(H3,23,24,25,26)/t10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p1103/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as requ...				US Patent US9512114 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PWS
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