Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM25084 (3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]ph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 235 | n/a | n/a | n/a | n/a | 7.4 | 22 |
TargeGen Inc. | Assay Description The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ... | J Med Chem 50: 4279-94 (2007) Article DOI: 10.1021/jm051056c BindingDB Entry DOI: 10.7270/Q2D798QW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM25084 (3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]ph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 235 | n/a | n/a | n/a | n/a | 7.4 | 22 |
TargeGen Inc. | Assay Description The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ... | Proc Natl Acad Sci U S A 103: 19866-71 (2006) Article DOI: 10.1073/pnas.0606956103 BindingDB Entry DOI: 10.7270/Q2J101GM | |||||||||||
More data for this Ligand-Target Pair |