Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM457842'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM457842 ((S)-2-(1-((6-amino-5-(3-methyl-1,2,4-oxadiazol-5-y...) Show SMILES CC#Cc1cccc2nc([C@H](C)Nc3ncnc(N)c3-c3nc(C)no3)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C26H22N8O2/c1-4-9-17-10-8-13-19-20(17)26(35)34(18-11-6-5-7-12-18)24(32-19)15(2)30-23-21(22(27)28-14-29-23)25-31-16(3)33-36-25/h5-8,10-15H,1-3H3,(H3,27,28,29,30)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as...				US Patent US10751339 (2020) BindingDB Entry DOI: 10.7270/Q2GX4FM7
					More data for this Ligand-Target Pair