Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM124761'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM124761 (US8765940, 1'-(7-fluoro-3-methyl-2-(4-methyl-2...) Show SMILES Cc1ccnc(c1)-c1nc2cc(F)ccc2c(N2CC3(CCOCC3)c3ncc(cc23)N2CCOCC2)c1C Show InChI InChI=1S/C31H32FN5O2/c1-20-5-8-33-26(15-20)28-21(2)29(24-4-3-22(32)16-25(24)35-28)37-19-31(6-11-38-12-7-31)30-27(37)17-23(18-34-30)36-9-13-39-14-10-36/h3-5,8,15-18H,6-7,9-14,19H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.19	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
Amgen Inc. US Patent					Assay Description A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...				US Patent US8765940 (2014) BindingDB Entry DOI: 10.7270/Q2WW7G94
					More data for this Ligand-Target Pair