Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM125438'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM125438 (US8772480, 293) Show SMILES C[C@@H](N1CCN(C[C@@H]1C)S(C)(=O)=O)c1cnc(Nc2ccc3scnc3c2)c(c1)-c1nc(C)nc(N)n1 |r| Show InChI InChI=1S/C24H29N9O2S2/c1-14-12-32(37(4,34)35)7-8-33(14)15(2)17-9-19(23-28-16(3)29-24(25)31-23)22(26-11-17)30-18-5-6-21-20(10-18)27-13-36-21/h5-6,9-11,13-15H,7-8,12H2,1-4H3,(H,26,30)(H2,25,28,29,31)/t14-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair