Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM130064'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM130064 (US8815918, 47) Show SMILES COc1cncc(c1)-c1nn2c(cnc2s1)-c1cnc(N)c(c1)C(F)(F)F Show InChI InChI=1S/C16H11F3N6OS/c1-26-10-2-9(4-21-6-10)14-24-25-12(7-23-15(25)27-14)8-3-11(16(17,18)19)13(20)22-5-8/h2-7H,1H3,(H2,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	25
Centro Nacional de Investigaciones Oncologicas (CNIO) US Patent					Assay Description The kinase activity was measured by using the commercial ADP Hunter Plus assay available from DiscoveRx (#33-016), which is a homogeneous assay to me...				US Patent US8815918 (2014) BindingDB Entry DOI: 10.7270/Q2251GWS
					More data for this Ligand-Target Pair